Ensembl Chimp

 

What's New in Ensembl 35

  • Re-numbering of Chimp chromosomes

    The Chimp chromosome numbers have been changed to the new primate standard proposed by E.H.
    Read more...

  • Compara database

    The compara orthology build has been updated to include the new Opossum genome, and chimp dnafrag names have been changed to take account of the re-numbering of the Chimp chromosomes (see Chimp news for more information).
    Read more...

  • Variation database

    All variation databases now include the new consequence_type 'REGULATORY_REGION'.

  • Genes on Featureview

    Features which have accompanying Gene locations, e.g. some AffyProbes, now display a table of gene names and descriptions at the top of the view page. See an example....

  • New species - Opossum
    Ensembl is pleased to announce the completion of the genebuild for the grey short-tailed opossum, Monodelphis domestica, based on assembly 2.0 from the Broad Institute.
    Read more...

More news...

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About the Chimp genome

Assembly

chimpanzeeThis site provides a data set based on the November 13th 2003 4x shotgun assembly from the Chimpanzee Sequencing Consortium headed by the GSC (St. Louis) and The Broad Institute (MIT).

The assembly is a merge of a "modified de novo" (MDN) assembly from the ARACHNE group, which used the human genome to establish that particular inserts were not chimeric, and a separate "validated chimp-on-human" (VCH) assembly which took the chimp reads which align uniquely to human, formed them into contigs via this alignment, and removed contigs which failed a two-haplotype consistency check.

Shared reads were used to align the two assemblies to each other, and where they were consistent, the VCH sequence was transferred to the MDN, resulting in the released merged assembly.

This release of the assembly has the following properties:

  • 361782 contigs, having N50 length 15.7 Kb
  • contig length total 2.73 Gb, spanning 3.02 Gb
  • 37849 supercontigs, having N50 length 8.6 Mb (not including gaps).

Chromosome numbering

As of Release 35 we have changed the chimpanzee chromosome numbering to match the new primate standard proposed by E.H. McConkey (Cytogenetics and Genome Research, 105:157-158) and endorsed by the International Chimpanzee Genome Consortium.

Annotation

The genome was aligned to human by UCSC using BLASTz. These alignments were used to transfer human gene structures (Human Build 34d) to chimpanzee. Owing to the low coverage commensurate with a 4x shotgun, there will inevitably be some mis-assemblies and mis-placements; however with better data it is expected that most chimpanzee genes will align with near-identical human genes.

Statistics

Assembly: PanTro 1.0, Nov 2003
Genebuild: Ensembl, Mar 2005
Database version: 35.3
Gene predictions : 22,475
Genscan gene predictions: 129,588
Gene exons: 226,066
Gene transcripts: 43,000
Base Pairs: 2,733,948,177
Golden Path Length: 2,733,223,211
Most common InterPro domains: Top 40 Top 500

 

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Ensembl v35 - Nov 2005
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