Top 40 InterPro Domains in the Ensembl Database| No. | Interpro name | Number of genes | Number of Ensembl hits | No. | Interpro name | Number of genes | Number of Ensembl hits |
|---|---|---|---|---|---|---|---|
| 1 | IPR001472 Bipartite nuclear localization signal |
1611 | 19834 | 21 | IPR001064 Beta and gamma crystallin |
100 | 2394 |
| 2 | IPR000694 Proline-rich region |
1060 | 16188 | 22 | IPR001092 Basic helix-loop-helix dimerization domain bHLH |
98 | 711 |
| 3 | IPR000719 Protein kinase |
787 | 12036 | 23 | IPR000152 Aspartic acid and asparagine hydroxylation site |
94 | 20813 |
| 4 | IPR000276 Rhodopsin-like GPCR superfamily |
650 | 21538 | 24 | IPR001356 Homeobox |
89 | 768 |
| 5 | IPR000477 RNA-directed DNA polymerase (Reverse transcriptase) |
604 | 1569 | 25 | IPR002110 Ankyrin |
85 | 1817 |
| 6 | IPR001687 ATP/GTP-binding site motif A (P-loop) |
498 | 10789 | 26 | IPR002198 Short-chain dehydrogenase/reductase SDR |
80 | 1820 |
| 7 | IPR002965 Proline-rich extensin |
281 | 1797 | 27 | IPR000047 Helix-turn-helix motif, lambda-like repressor |
80 | 905 |
| 8 | IPR000345 Cytochrome c heme-binding site |
246 | 14465 | 28 | IPR001841 Zn-finger, RING |
79 | 317 |
| 9 | IPR000337 G-protein coupled receptors family 3 (Metabotropic glutamate receptor-like) |
186 | 7287 | 29 | IPR000357 HEAT repeat |
78 | 1218 |
| 10 | IPR000504 RNA-binding region RNP-1 (RNA recognition motif) |
183 | 3208 | 30 | IPR000048 IQ calmodulin-binding region |
78 | 4557 |
| 11 | IPR007110 Immunoglobulin-like |
181 | 568 | 31 | IPR000169 Eukaryotic thiol (cysteine) protease |
76 | 2212 |
| 12 | IPR001230 Prenyl group binding site (CAAX box) |
159 | 2503 | 32 | IPR002048 Calcium-binding EF-hand |
75 | 904 |
| 13 | IPR001680 G-protein beta WD-40 repeat |
155 | 3721 | 33 | IPR001878 Zn-finger, CCHC type |
72 | 225 |
| 14 | IPR000008 C2 domain |
148 | 4218 | 34 | IPR001128 Cytochrome P450 |
68 | 6063 |
| 15 | IPR000315 Zn-finger, B-box |
128 | 4431 | 35 | IPR000379 Esterase/lipase/thioesterase, active site |
65 | 1368 |
| 16 | IPR000210 BTB/POZ domain |
116 | 4358 | 36 | IPR000051 SAM (and some other nucleotide) binding motif |
64 | 329 |
| 17 | IPR000068 Extracellular calcium-sensing receptor |
115 | 11611 | 37 | IPR001254 Serine protease, trypsin family |
64 | 1683 |
| 18 | IPR001440 TPR repeat |
112 | 2108 | 38 | IPR000198 RhoGAP domain |
61 | 855 |
| 19 | IPR007087 Zn-finger, C2H2 type |
112 | 4289 | 39 | IPR000194 H+-transporting two-sector ATPase, alpha/beta subunit, central region |
55 | 2572 |
| 20 | IPR001611 Leucine-rich repeat |
105 | 1385 | 40 | IPR007086 Zn-finger, C2H2 subtype |
54 | 5343 |
View top 500 InterPro hits (large table)
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